821995--3/13/2006--COLUMBIA_LABORATORIES

related topics

{product, candidate, development}

{stock, price, share}

{product, liability, claim}

{customer, product, revenue}

{operation, international, foreign}

{personnel, key, retain}

{property, intellectual, protect}

{regulation, change, law}

{tax, income, asset}

{provision, law, control}

{control, financial, internal}

{product, market, service}

We have a history of losses and we may continue to incur losses. Our business is heavily dependent on the continued sale of Crinone . If revenues from these partnered products fail to increase as anticipated, or materially decline, our financial condition and results of operations will be materially harmed. Our Marketing Agreement for Prochieve may be terminated under certain circumstances. Healthcare insurers and other payors may not pay for our products or may impose limits on reimbursement. We face significant competition from pharmaceutical and consumer product companies, which may adversely impact our market share. Our products could demonstrate hormone replacement risks. We may be exposed to product liability claims. Steps taken by us to protect our proprietary rights might not be adequate, in which case competitors may infringe on our rights or develop similar products. The United States and foreign patents upon which our original We are subject to government regulation, which could affect our ability to sell products. The development of our pharmaceutical products, including the development of Prochieve 8% for the prevention of preterm birth, is uncertain and subject to a number of significant risks. We may experience adverse events in clinical trials, which could delay or halt our product development. Delays or failures in obtaining regulatory approvals may delay or prevent marketing of the products that we are developing. We are dependent on a principal supplier, the loss of which could impair our ability to manufacture and sell our products. We are dependent upon third-party developers and manufacturers, the loss of which could result in a loss of revenues. The loss of our key executives could have a significant impact on our company. We may be limited in our use of our net operating loss carryforwards. Sales of large amounts of common stock may adversely affect our market price. The issuance of preferred stock may adversely affect rights of common stockholders Changes in, or interpretations of, accounting principles could result in unfavorable accounting charges. We do not intend to pay cash dividends on our common stock. As a result, you will not receive any periodic in come from an investment in our common stock. Anti-takeover provisions could impede or discourage a third-party acquisition of our company. This could prevent stockholders from receiving a premium over market price for their stock. We are exposed to market risk from foreign currency exchange rates.

Full 10-K form ▸

821995--3/13/2006--COLUMBIA_LABORATORIES_INC