920465--3/31/2009--LA_JOLLA_PHARMACEUTICAL_CO

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{stock, price, share}

{stock, price, operating}

{tax, income, asset}

{cost, regulation, environmental}

We recorded an impairment loss for the year ended December 31, 2008 and may need to record additional charges in the future. We face environmental liabilities related to certain hazardous materials used in our operations. II. RISK FACTORS RELATED SPECIFICALLY TO OUR STOCK. The price of our common stock has been volatile and has declined significantly and we may face delisting from Nasdaq. Our common stock price is volatile and may continue to decline.

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